"SILVAMP TB LAM" rapid urine tuberculosis test predicts mortality in patients hospitalized with human immunodeficiency virus in South Africa.

Sossen, Bianca; Broger, Tobias; Kerkhoff, Andrew D; Schutz, Charlotte; Trollip, Andre; Moreau, Emmanuel; Schumacher, Samuel G; Burton, Rosie; Ward, Amy; Wilkinson, Robert J; Barr, David A; Nicol, Mark P; Denkinger, Claudia M; Meintjes, Graeme

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"SILVAMP TB LAM" rapid urine tuberculosis test predicts mortality in patients hospitalized with human immunodeficiency virus in South Africa.

journal contribution

posted on 2020-11-12, 11:03 authored by Bianca Sossen, Tobias Broger, Andrew D Kerkhoff, Charlotte Schutz, Andre Trollip, Emmanuel Moreau, Samuel G Schumacher, Rosie Burton, Amy Ward, Robert J Wilkinson, David A Barr, Mark P Nicol, Claudia M Denkinger, Graeme Meintjes

Reducing diagnostic delay is key towards decreasing tuberculosis-associated deaths in people living with HIV. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86-97%.