The Francis Crick Institute
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Rapid task-dependent tuning of the mouse olfactory bulb

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journal contribution
posted on 2019-12-16, 17:39 authored by Anzhelika Koldaeva, Andreas T Schaefer, Izumi Fukunaga
Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area of the mouse, the olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way.