elife-43558-v1.pdf (2.02 MB)
Rapid task-dependent tuning of the mouse olfactory bulb
journal contributionposted on 2019-12-16, 17:39 authored by Anzhelika Koldaeva, Andreas T Schaefer, Izumi Fukunaga
Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area of the mouse, the olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way.