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Quantification of biomarker functionality predicts patient outcomes.

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journal contribution
posted on 11.05.2021, 13:24 by Banafshé Larijani, James Miles, Stephen G Ward, Peter J Parker
Implementation of a quantitative molecular imaging method (iFRET), which determines receptor-ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.

Funding

Crick (Grant ID: 10130, Grant title: Parker FC001130)

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