The Francis Crick Institute
journal.pbio.3002576.pdf (3.44 MB)

One size does not fit all: Lysosomes exist in biochemically and functionally distinct states.

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journal contribution
posted on 2024-04-11, 11:03 authored by Claudio Bussi, Maximiliano G Gutierrez
Single-organelle resolution approaches have the potential to advance our knowledge of the heterogeneity of lysosome function. Challenging population-based models, we propose a "lysosome states" concept that links single lysosomes to function.


Crick (Grant ID: CC2081, Grant title: Gutierrez CC2081) European Research Council (Grant ID: 772022 - DynaMO_TB, Grant title: ERC 772022 - DynaMO_TB)