Detection of T-cadherin expression in mouse embryos
journal contributionposted on 2020-09-09, 10:40 authored by KA Rubina, VA Smutova, ML Semenova, AA Poliakov, S Gerety, D Wilkinson, EI Surkova, EV Semina, V Yu Sysoeva, VA Tkachuk
© 2015 Park-media, Ltd. The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.