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Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes

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posted on 15.01.2020 by Thomas Lanyon-Hogg, Markus Ritzefeld, Lea Sefer, Jasmine K Bickel, Amalie F Rudolf, Nattawadee Panyain, Ganka Bineva-Todd, Cory A Ocasio, Nicola O'Reilly, Christian Siebold, Anthony I Magee, Edward W Tate

A highly accurate and versatile fluorescence polarisation assay for any enzyme adding or removing lipid posttranslational modifications, with the potential to accelerate drug discovery against these targets.

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Crick (Grant ID: 10013, Grant title: O'Reilly FC001999)

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