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Figure 1A.tif (4.39 MB)
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Figure 1C.tif (7.64 MB)
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Figure 1D.tif (7.64 MB)
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Figure 2B-6.tif (7.64 MB)
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Figure 2B-16.tif (7.64 MB)
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Figure 2C.tif (7.63 MB)
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Figure 3C-E_High_Nsp15 screen results.xlsx (1.01 MB)
DATASET
Figure 3C-E_Low_Nsp15 screen results.xlsx (1.02 MB)
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Figure 3C-E_Nsp15 screen analysis script.R (16.35 kB)
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Figure 3C-E_Nsp15 screen normalised results.xlsx (949.27 kB)
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Figure 4B.tif (12.19 MB)
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Figure 4C.tif (10.41 MB)
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Figure 5A_NSC_titr_cells.png (235.71 kB)
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Figure 5A_NSC_titr_virus.png (15.23 kB)
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Figure 5C_NSC_titr_cells.png (281.9 kB)
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Figure 5C_NSC_titr_virus.png (110.16 kB)
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Figure 5E_NSC_titr_rem_cells.png (281.77 kB)
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Figure 5E_NSC_titr_rem_virus.png (53.73 kB)
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Figure S1B.tif (5.35 MB)
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Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp15 Endoribonuclease
dataset
posted on 2021-07-05, 13:14 authored by Berta CanalBerta Canal, Ryosuke Fujisawa, Tom D Deegan, Allison Mcclure, John DiffleyJohn DiffleyThis entry contains datasets and raw images associated to the following manuscript: "Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp15 Endoribonuclease", Canal et al., Biochem Journal, 2021
Data files are labelled accordingly to the different Figures and Supplementary figures of the manuscript and include:
- Screen data of the raw results of the screen at both concentrations, the normalised results, the script we created for the analysis. See manuscript for further information.
- Gel and microscopy images.
