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1A-G_Summary gels in Figure 1.ai (7.09 MB)
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1A_gel 3.jpg (20.45 kB)
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1A_gel 4.jpg (59.12 kB)
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1C and 1G_gel 5.tif (11 MB)
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1D_gel 6.tif (11 MB)
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1D_gel 7.tif (11 MB)
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1E_gel 8.jpg (131.76 kB)
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1E_gel 9.jpg (125.72 kB)
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1F_gel 10.tif (11 MB)
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3B,C_Summary gels in Figure 3.ai (3.11 MB)
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3B_gel 1.jpg (131.62 kB)
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3B_gel 2.jpg (45.73 kB)
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3C_gel 3.jpg (138.13 kB)
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4F,G_1.25uM second screen_original.xlsx (784.68 kB)
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4F,G_1.25uM second screen_upsidedown plates corrected.xlsx (794.01 kB)
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4F,G_3.75uM second screen_original.xlsx (784.85 kB)
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4F,G_Analysis script second screen.R (17.83 kB)
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4F,G_Normalised data second screen.xlsx (919.89 kB)
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51 files

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease

dataset
posted on 2021-07-05, 13:14 authored by Berta CanalBerta Canal, Allison Mcclure, Joseph CurranJoseph Curran, John DiffleyJohn Diffley
This entry contains datasets and raw images associated to the following manuscript: "Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease", Canal et al., Biochem Journal, 2021

Data files are labelled accordingly to the different Figures or Supplementary figures of the manuscript and include:

- Screen data of the raw results of the two screens at both concentrations, the normalised results, the script we created for the analysis, and the plate distribution. See manuscript for further information.

- Gel and microscopy images.

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