Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase
datasetposted on 05.07.2021, 13:18 by Agustina BertolinAgustina Bertolin, Florian WeissmannFlorian Weissmann, Jingkun ZengJingkun Zeng, John DiffleyJohn Diffley
This entry contains screen datasets and raw images associated to the following manuscript: "Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase", Zeng et al, Biochem Journal, 2021
The Data include:
-Excel files with description of the chemical library and reaction velocity and endpoint analysis of screen results obtained in the screen to identify inhibitors of nsp13 helicase of SARS-CoV-2. Please see Material and methods, Data analysis.
We also added for each selected compound the kinetic curves of the selected compounds (red) + compounds in the adjacent wells (black).
-Raw gel images (Fig 4G, Supp Fig 1C, Supp Fig 2C)