The Francis Crick Institute
Browse

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase

dataset
posted on 2021-07-05, 13:18 authored by Agustina BertolinAgustina Bertolin, Florian WeissmannFlorian Weissmann, Jingkun Zeng, John DiffleyJohn Diffley
<div>This entry contains screen datasets and raw images associated to the following manuscript: "Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase", Zeng et al, Biochem Journal, 2021</div><div><br></div><div>The Data include:<br></div><div>-Excel files with description of the chemical library and reaction velocity and endpoint analysis of screen results obtained in the screen to identify inhibitors of nsp13 helicase of SARS-CoV-2. Please see Material and methods, Data analysis.<br></div><div><br></div><div>We also added for each selected compound the kinetic curves of the selected compounds (red) + compounds in the adjacent wells (black).</div><div> </div><div>-Raw gel images (Fig 4G, Supp Fig 1C, Supp Fig 2C)<br></div>

History

Usage metrics

    Data

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC