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Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp12/7/8 RNA-dependent RNA Polymerase
dataset
posted on 2021-07-05, 13:18 authored by Agustina BertolinAgustina Bertolin, Florian WeissmannFlorian Weissmann, Jingkun ZengJingkun Zeng, John DiffleyJohn DiffleyThis entry contains screen datasets and raw images associated to the following manuscript: "Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp12/7/8 RNA-dependent RNA Polymerase", Bertolin et al, Biochem Journal, 2021
The data include:
-Excel files with reaction velocity and endpoint analysis of screen results obtained in the screen to identify inhibitors of nsp12/7/8 RdRp of SARS-CoV-2.
Please see Material and methods, Data analysis.
-Raw images of gels (Fig 1C, 5B, 5C)
