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Data and analysis code for Rodrigues et al., PLoS Biology (2024)

dataset
posted on 2024-11-01, 15:39 authored by Nathan GoehringNathan Goehring, Nelio Lacerda Rodrigues, Tom Bland, Nisha HiraniNisha Hirani, Kangbo NgKangbo Ng

This repository includes code and data associated with the following manuscript:

Rodrigues et al. (2024). Quantitative perturbation-phenotype maps reveal nonlinear responses underlying robustness of PAR-dependent asymmetric cell division. PLoS Biology. doi: https://doi.org/10.1371/journal.pbio.3002437

It includes the following:

Analysis code (Folder: SourceCode-2024-Rodrigues-PLOS)

  • par-segmentation-0.1.16.zip
  • 2024-Rodrigues-PLOS-PLOS_final_submission.zip
  • Most recent versions also available at https://github.com/goehringlab/

Experimental Source Data (Folder: SourceData-2024-Rodrigues-PLOS).

  • All underlying quantitative data for Fig. 2-8, S1, S2.

Please see manuscript and included documentation for details.

Funding

Polarity and Patterning Networks Laboratory

Cancer Research UK

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