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Data and analysis code for Bland et al., EMBO J (2024)

dataset
posted on 2024-06-24, 14:45 authored by Tom Bland, Nisha HiraniNisha Hirani, David BriggsDavid Briggs, Kangbo NgKangbo Ng, Riccardo Rossetto, Neil McDonaldNeil McDonald, David Zwicker, Nathan GoehringNathan Goehring

This repository includes all code and data required to reproduce the analysis in the following manuscript:

Bland et al. Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity. EMBO J (2024). doi: 10.1038/s44318-024-00123-3.

It includes the following:

Modeling and analysis code (Code-2024-Bland-EMBO-EMBO_final_release, also available at https://github.com/goehringlab/2024-Bland-EMBO/releases/tag/EMBO_final).

Experimental Source Data (Folder: SourceData-2024-Bland-EMBO).

Some source data is provided in an alternative format at:

https://www.ebi.ac.uk/biostudies/sourcedata/studies/S-SCDT-10_1038-S44318-024-00123-3

Please see manuscript and included documentation for details.

Funding

Polarity and Patterning Networks Laboratory

Cancer Research UK

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Signalling and Structural Biology Laboratory

Cancer Research UK

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Integrated simulations of active emulsions in complex environments

European Research Council

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History